TwittX has many option available to you without digging through tons of pages.
Silver Bird Plus is a Twitter client for Google Chrome.
Notifier for Twitter is a fully-fledged Twitter client for your browser.
A client to post twitter updates/messages from your desktop.
Witty Twitter, jongalloway
Witty is a free, open source Twitter client for Windows.
DestroyTwitter is a Twitter client, not an every-social-network-in-the-world.
An elegant, simple-to-use Twitter client for Windows XP and above.
Twitcher is a Twitter client that allow you access to your twitter account.
Twittastic, is a Twitter client meant to do it better for most of the users.
digiTweet is an open source desktop Twitter client for Windows.
TweetCraft is an in-game Twitter client for World of Warcraft.
jake stevenson, roel van den brand, dirk rettschlag, lifanxi
PockeTwit is a twitter client for your desktop pc.
TweetPocket, MOBENT, LLC.
TweetPocket is another Twitter client based on Adobe AIR.
Textwit is a simple and powerful new Twitter client for Windows.
SharedMinds Desktop is a Twitter client for Windows.
Dave Briccetti Software Consulting
TalkingPuffin is a powerful, open source, desktop Twitter client.